Antimicrobial activities of Syzygium cumini leave extracts against selected microorganisms

A. G Elfadil, Awad Abdalfattah karamallah, Ahmed Mahgoub Abualhassan, Abed Alaziz Hamid, M.K. Sabahelkhier

Abstract


Leaves extracts of Syzygium cumini (L) were collected to test their antimicrobial activity. The collected materials were extracted by petroleum ether, methanol and water by using different concentration (15% 10% and 5%). Were obtained and bioassay in vitro for its bioactivity to inhabit the growth of four types of bacteria,namely; (Staphlococcus aureus, Escherichia coli, Pseudomonas aeruginosa, and Bacillus subitils) and two types of fungi (Aspergillus niger, and Candida albicans). The extract of Syzygium cumini leaves showed different activity against the selected bacteria at all concentration levels. By using cup plate diffusion method, petroleum ether extract of Syzygium cumini leaves showed activity against E. coli only. Methanol extract showed variable activity against bacteria in different concentrations especially 15% concentration showed high activity against B. subtilis. Water extract showed variable activity against most of the tested bacteria. E. coli was found to be sensitive to all concentrations.


Full Text:

PDF

References


Anirban R, Sanjib B, P. JN, Biswas M. India Alternative Medicine Studies. West Bengal: Bengal Institute of Pharmaceutical Sciences; 2011.

Organization WH. WHO traditional medicine strategy 2002-2005. 2002.

Mohanty B, Behera B, Sharma A. Nutritional significance of small indigenous fishes in human health. 2011.

Zaman K. Medicinal plants with hypoglycemic activity. Journal of Ethnopharmacology. 1989;26:1-55.

Kubin C. Infectious Diseases Introduction to Antimicrobial Therapy: Clinical Pharmacist; 2005.

Noble G, Sue J. Antibiotics (Anti-Microbial). Swansea: University of Wales 2005.

Andrews JM. Determination of minimum inhibitory concentrations. Journal of antimicrobial Chemotherapy. 2001;48:5-16.

Nambiar VPK. Indian medicinal plants: a compendium of 500 species: Orient Blackswan; 1996.

Bhandary M, Chandrashekar K, Kaveriappa K. Medical ethnobotany of the siddis of Uttara Kannada district, Karnataka, India. Journal of Ethnopharmacology. 1995;47:149-58.

Ayyanar M, Subash-Babu P. Syzygium cumini (L.) Skeels: A review of its phytochemical constituents and traditional uses. Asian Pacific Journal of Tropical Biomedicine. 2012;2:240-6.

Teixeira CC, Pinto LP, Kessler FHP, Knijnik L, Pinto CP, Gastaldo GJ, et al. The effect of Syzygium cumini (L.) skeels on post-prandial blood glucose levels in non-diabetic rats and rats with streptozotocin-induced diabetes mellitus. Journal of Ethnopharmacology. 1997;56:209-13.

Valencia IC, Kirsner RS, Kerdel FA. Microbiologic evaluation of skin wounds: alarming trend toward antibiotic resistance in an inpatient dermatology service during a 10-year period. Journal of the American Academy of Dermatology. 2004;50:845-9.

Miles A, Misra S, Irwin J. The estimation of the bactericidal power of the blood. Journal of Hygiene. 1938;38:732-49.

Cheesbrough M. District laboratory practice in tropical countries: Cambridge university press; 2006.

Kavanagh F. Analytical microbiology: Elsevier; 2014.




DOI: http://dx.doi.org/10.20286/nova-jmbs-040245

Refbacks

  • There are currently no refbacks.


Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Nova Journal of Medical and Biological Sciences ISSN 2292-793X (Online) Published by Nova Pub inc.

Nova Explore Publications
is a member of CrossRef.
DOI Prefix: 10.20286