An overview of the effects of antibiotics and medicinal plant extracts on the human microflora

Emad Mohamed Abdallah

Abstract


The biological interactions of the microflora in the human body are essential to maintain the somatic eco-physiological balance. Antibiotics, which are considered as a panacea against pathogens without knowing how it influences the microflora, could create a disease by disturbing the microbial ecosystem of the human body and develop new generations of antibiotics resistant pathogens. Medicinal plants could get rid the pathogens and also maintain the normal flora. There is a necessity to preserve the micoflora ecosystem, by means different approaches such as support the antibiotic treatment with some renovated compounds like natural medicinal compounds or probiotics, more comprehensive studies in this issue are badly needed.


Full Text:

PDF

References


Davis CP. Normal Flora. In: Baron S, editor. Medical Microbiology.4th edition. Galveston (TX): University of Texas Medical Branch at Galveston; 1996. Chapter 6. http://www.ncbi.nlm.nih.gov/books/NBK7617/

Edlund C, Nord CE. Effect on the human normal microflora of oral antibiotics for treatment of urinary tract infections.Journal of antimicrobial chemotherapy. 2000; 46(S1): 41-48. PMID:11051623

Ahn YJ, Sakanaka S, Kim M-J, kawamura T, Fujisawa T, Mitsuoka T. Effect of Green Tea Extract on Growth of Intestinal Bacteria. Microbiological Ecology in Health and Disease.1990; 3: 335-338.

TodarT . Todar's Online Textbook of Bacteriology 2000. www.textbookofbacteriology.net

Tanock CW. The normal microflora: an introduction. In: Gerald W. Tannock, editor, Medical Importance of the Normal Microflora. Chapter 1, Springer-Science and Business Media, B.V., Dordrecht, Germany; 1999.pp.1-20.

McFarland LV. Normal flora: diversity and functions. Microbial Ecology in Health and Disease 2000; 12: 193–207.

Heiman ML, Greenway FL. A healthy gastrointestinal microbiome is ependent on dietary diversity. Molecular Metabolism. 2016; 5: 317-320.doi: 10.1016/j.molmet.2016.02.005

Abdallah EM. Plants: An alternative source for antimicrobials. Journal of Applied Pharmaceutical Science. 2011; 1 (6): 16-20 .

Davies J, Davies D. Origins and Evolution of Antibiotic Resistance. Microbiology and Molecular Biology Reviews.2010; 417-433.

Sorum H, Sunde M. Resistance to antibiotics in the normal flora of animals.Veterinary Research.2001; 32: 227–241.

Abeles SR, Jones MB, Santiago-Rodriguez TM, Ly M, Klitgord N, Yooseph S, Nelson KT, Pride DT. Microbial diversity in individuals and their household contacts following typical antibiotic courses.Microbiome. 2016; 4(39): 1-12. PMCID: PMC4967329 DOI: 10.1186/s40168-016-0187-9

Jernberg C, Lofmark S, Edlund C, Jansson JK. Long-term impacts of antibiotic exposure on the human intestinal microbiota.Microbiology.2010; 156: 3216–3223. PMID: 20705661 DOI:10.1099/mic.0.040618-0

Dhama K, Tiwari R, Chakraborty S, Saminathan M, Kumar A, et al. Evidence based antibacterial potentials of medicinal plants and herbs countering bacterial pathogens especially in the era of emerging drug resistance: An integrated update. International Journal of Pharmacology.2014; 10: 1-43.doi: 10.3923/ijp.2014.1.43

Rios JL, Recio MC. Medicinal plants and antimicrobial activity. Journal of Ethnopharmacology. 2005; 100(1-2):80-84. doi:10.1016/j.jep.2005.04.025

Sagar S. Role of natural toothbrushes in containing oral microbial flora-A review. Asian Journal of Pharmaceutical and Clinical Research. 2015; 8(4): 29-33.

Weerakkody NS, Caffin N, Dykes GA, Turner MS. Effect of antimicrobial spice and herb extract combinations on Listeria monocytogenes, Staphylococcus aureus, and spoilage microflora growth on cooked ready-to-eat vacuum-packaged shrimp. Journal of Food Protection, 2011; 74(7):1119-1125. doi: 10.4315/0362-028X.JFP-11-052.

Webley D, Eastwood D, Gimingham C. Development of a Soil Microflora in Relation to Plant Succession on Sand-Dunes, Including the `Rhizosphere' Flora Associated with Colonizing Species. Journal of Ecology. 1952; 40(1): 168.

Krasil'nikov NA. Soil microorganisms and higher plants.Academy of Sciences of the USSR Institute of Microbiology. Moscow. 1958.

Ryan RP, Germaine K, Franks A, Ryan D, Dowling DN. Bacterial endophytes: recent developments and applications. FEMS Microbiol Lett.2008; 278: 1–9. PMID: 18034833 DOI: 10.1111/j.1574-6968.2007.00918.x

Phoem AN, Voravuthikunchai SP. Growth stimulation/inhibition effect of medicinal plants on human intestinal microbiota. Food SciBiotechnol.2012; 21: 739. doi: 10.3390/toxins5112009

Tijjani A. Antibiotic-Plant Synergy as a New Strategy for Combating Drug Resistant Bacteria. In: A. Mendez-Vilas, editor, Microbial pathogens and strategies for compating them, science, technology and education. Microbiology book series, Vol.4.Formatex Research Center, Spain. Vol.2, 2013. pp. 834-837.

Adwan G, Mhanna M. Synergistic Effects of Plant Extracts and Antibiotics on

Staphylococcus aureus Strains Isolated from Clinical Specimens. Middle-East Journal of Scientific Research. 2008; 3 (3): 134-139.

Doron S, Snydman DR. Risk and Safety of Probiotics. Clinical Infectious Diseases. 2015; 60 (S2): 129-134. PMID: 25922398 PMCID: PMC4490230 DOI: 10.1093/cid/civ085

Dwivedi GR, Sanchita, Singh DP, Sharma A, Darokar MP, Srivastava SK. Nano Particles: Emerging Warheads Against Bacterial Superbugs. Current Topics in Medical Chemistry. 2016; 16(18):1963-1975. PMID: 26876525




DOI: http://dx.doi.org/10.20286/nova-jmbs-050308

Refbacks

  • There are currently no refbacks.


Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Nova Journal of Medical and Biological Sciences ISSN 2292-793X (Online) Published by Nova Pub inc.

Nova Explore Publications
is a member of CrossRef.
DOI Prefix: 10.20286